Datasets:

ClarusC64
/

ABX-HT-005_neurotoxicity_threshold_shift-v0.1

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train · 10 rows

row_id string	series_id string	timepoint_h int64	host_model string	drug string	plasma_conc_mg_L float64	csf_conc_mg_L float64	expected_csf_conc_mg_L float64	csf_deviation float64	bbb_penetration_ratio float64	expected_bbb_ratio float64	ratio_deviation float64	neuro_marker_index float64	neuro_coherence_index float64	exposure_index float64	stress_index float64	later_severe_neuro_flag int64	assay_method string	source_type string	neuro_threshold_shift_signal int64	earliest_neuro_threshold_shift int64	notes string
ABXHT005-TR-0001	S1	0	human_sim	cefepime	10	0.5	0.5	0	0.05	0.05	0	0.1	0.9	0.1	0.1	0	pk_csf_neuro_panel	simulated	0	0	baseline
ABXHT005-TR-0002	S1	12	human_sim	cefepime	12	0.6	0.6	0	0.05	0.05	0	0.12	0.88	0.85	0.9	0	pk_csf_neuro_panel	simulated	0	0	tracks expected
ABXHT005-TR-0003	S1	24	human_sim	cefepime	12	1.1	0.6	0.5	0.092	0.05	0.042	0.55	0.35	0.9	0.9	0	pk_csf_neuro_panel	simulated	0	0	first shift
ABXHT005-TR-0004	S1	36	human_sim	cefepime	12	1.3	0.6	0.7	0.108	0.05	0.058	0.62	0.3	0.9	0.9	0	pk_csf_neuro_panel	simulated	1	1	confirmed onset
ABXHT005-TR-0005	S1	72	human_sim	cefepime	12	2.4	0.6	1.8	0.2	0.05	0.15	0.85	0.2	0.9	0.9	1	pk_csf_neuro_panel	simulated	1	0	severe later
ABXHT005-TR-0006	S2	0	human_sim	meropenem	15	0.3	0.3	0	0.02	0.02	0	0.1	0.9	0.1	0.1	0	pk_csf_neuro_panel	simulated	0	0	baseline
ABXHT005-TR-0007	S2	24	human_sim	meropenem	16	0.32	0.32	0	0.02	0.02	0	0.12	0.86	0.9	0.9	0	pk_csf_neuro_panel	simulated	0	0	stable
ABXHT005-TR-0008	S2	48	human_sim	meropenem	16	0.33	0.33	0	0.021	0.02	0.001	0.12	0.84	0.9	0.9	0	pk_csf_neuro_panel	simulated	0	0	stable
ABXHT005-TR-0009	S3	0	human_sim	cefepime	10	1.8	0.5	1.3	0.18	0.05	0.13	0.7	0.3	0.9	0.9	1	pk_csf_neuro_panel	simulated	0	0	baseline ratio high
ABXHT005-TR-0010	S4	0	human_sim	cefepime	12	1.3	0.6	0.7	0.108	0.05	0.058	0.62	0.3	0.9	0.3	1	pk_csf_neuro_panel	simulated	0	0	stress low

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