---
dataset_info:
  features:
  - name: x
    dtype: string
  - name: y
    dtype: float32
  - name: targets
    dtype: string
  - name: aso_sequence_5_to_3
    dtype: string
  - name: inhibition_percent
    dtype: float32
  - name: chemistry_json
    dtype: string
  - name: custom_id
    dtype: string
  - name: target_mrna
    dtype: string
  - name: target_gene
    dtype: string
  - name: cell_line
    dtype: string
  - name: cell_line_species
    dtype: string
  - name: dosage
    dtype: float32
  - name: cells_per_well
    dtype: float32
  - name: transfection_method
    dtype: string
  - name: steric_blocking
    dtype: bool
  splits:
  - name: train
    num_bytes: 110977411
    num_examples: 190927
  download_size: 10132302
  dataset_size: 110977411
configs:
- config_name: default
  data_files:
  - split: train
    path: data/train-*
---

## Citation

This dataset is derived from the ASO Atlas resource introduced in Hill et al. (2025). If you use this dataset, please cite:

```bibtex
@article{hill2025accurately,
  title={Accurately modelling RNase H-mediated antisense oligonucleotide efficacy},
  author={Hill, Barney and Jaques, Maisie R and Nair, Remya R and Whiffin, Nicola and Wood, Matthew JA and Sanders, Stephan J and Oliver, Peter L and Hill, Alyssa C and Rinaldi, Carlo},
  journal={bioRxiv},
  pages={2025--10},
  year={2025},
  publisher={Cold Spring Harbor Laboratory}
}
```

## Source
GitHub: https://github.com/barneyhill/aso_atlas