<p>Microsoft <a href="http://weblogs.asp.net/scottgu/archive/2008/09/28/jquery-and-microsoft.aspx" rel="nofollow noreferrer">recently announced</a> that the Javascript/HTML DOM library <strong>jQuery will be integrated</strong> into the ASP.NET MVC framework and into ASP.NET / Visual Studio.</p>

<p>What is the best practice or strategy adopting jQuery using <strong>ASP.NET 2.0</strong>? I'd like to prepare a large, existing ASP.NET Web Application (<strong>not</strong> MVC) for jQuery. How would I deal with versioning and related issues?</p>

<p>Are the any caveats integrating jQuery and <strong>ASP.NET Ajax</strong>? Or <strong>3rd party components</strong> like Telerik or Intersoft controls?</p>

There's a small issue which is mentioned by David Ward here:
http://encosia.com/2008/09/28/avoid-this-tricky-conflict-between-aspnet-ajax-and-jquery/
But there should not be any major concerns about integrating jQuery into an existing application, you wouldn't notice major advantages unless you're planning a lot of updating/ reworking of existing code to take advantages of jQuerys power.