<p>I'm getting zits or blobs in lithophanes while printing on my Ender 3 and 10S Pro. I tried a suggestion: change resolution in mesh fixes of Cura to 0.5 (from 0.05 default). That removed the zits.</p>
<p>But now there are white patches as shown in the image. I reduced the resolution to 0.2 but to no avail.</p>
<p>Anyone else encountered this problem?</p>
<p><a href="https://i.stack.imgur.com/Xpqvz.jpg" rel="nofollow noreferrer" title="Example of white patches in a lithophane print"><img src="https://i.stack.imgur.com/Xpqvz.jpg" alt="Example of white patches in a lithophane print" title="Example of white patches in a lithophane print" /></a></p>
<p><a href="https://i.stack.imgur.com/tKl6c.jpg" rel="nofollow noreferrer" title="Example of zits/blobs in a lithophane print"><img src="https://i.stack.imgur.com/tKl6c.jpg" alt="Example of zits/blobs in a lithophane print" title="Example of zits/blobs in a lithophane print" /></a></p>

In short, no. A 2D image has insufficient information to determine a 3D form.
If you want to do this yourself, what you could do is start with the 2D outline in a program like Blender (as 0scar mentioned in a comment), extrude it to make a thin "cardboard cutout", then begin shaping it into three dimensions from there. Imagine it like cutting a slab of Play-doh with a cookie cutter matching your 2D outline, then using the picture and your imagination as a guide to form it into 3D. I'm not sure whether something like that makes any more sense than just starting from scratch modeling it.
Alternatively, nowadays there
might
be some "AI" models to produce a reasonable guess at what 3D structure you want, with the knowledge that it's supposed to be a person, for a 2D image you provide. I'm not sure if there's anything yet of usable quality, but it's something you could look for.