<p>My printer is calibrated for a certain clearance from the heated bed, which is chosen based on PLA.</p>

<p>I would like to try to increase it for the first layer for PETG, so that adhesion is reduced. The printer has M5 screws with 4000 steps/mm, so the resolution clearly allows that. </p>

<p>I don't want to modify the printer, I would like a G-Code or another option that I can apply in Prusa slicer in association with the specific filament when desired. I don't want to change the flow rate of the first layer, only the "zero" distance.</p>

<p>How can I do that?</p>

Maybe you would be better off with TPU or some other type of flexible material...
I have been able to print PLA and have it flex quite a bit, but that was an ~0.2mm single layer print, I guess maybe up to 0.3-0.4mm should still be a little bit flexible, but not much. Also since you want it to wipe things, maybe you should look if TPU even has all the properties required for that as Carl mentioned in the comments.