<p>Simple question, spurred on by the removal of the target attribute in HTML 4.0 Strict and XHTML 1.0 Strict.</p>

I personally don't think so, as web users become more savvy, they'll ask for a new window from the browser.  It annoys me when a website does this a lot.
I think the question is sort of subjective.  It could be good if you're launching a javascript game or something.
Here's
Neil Turner's reasons not to do it
.