<p>I've created a new C++ project in Visual Studio 2008.  No code has been written yet;  Only project settings have been changed.</p>

<p>When I compile the project, I receive the following fatal error:</p>

<blockquote>
  <p>fatal error LNK1104: cannot open file 'C:\Program.obj'</p>
</blockquote>

This particular issue is caused by specifying a dependency to a lib file that had spaces in its path.  The path needs to be surrounded by quotes for the project to compile correctly.
On the
Configuration Properties -> Linker -> Input
tab of the project’s properties, there is an
Additional Dependencies
property.  This issue was fixed by adding the quotes. For example, changing this property from:
C:\Program Files\sofware
sdk\lib\library.lib
To:
"C:\Program Files\sofware
sdk\lib\library.lib"
where I added the quotes.