<p>I finished the mount of my Anet A8, tested everything and apparently it was ok. I installed the driver that came with it, <code>CH341SER_MAC</code>, turned on the printer, connect USB cable, but nothing happened. </p>

<p>In Cura, I tried to add a printer many times and this message always appears</p>

<blockquote>
  <p>The printer isn't connected. </p>
</blockquote>

<p>In OSX, I discover in System Information, an <strong>USB2.0-Serial</strong>, that I think can be the printer.  Is it a printer driver problem? Is it the Cura setting? I'm completely lost...</p>

<p><a href="https://i.stack.imgur.com/wyfZ6.png" rel="nofollow noreferrer" title="OSX System Information - USB"><img src="https://i.stack.imgur.com/wyfZ6.png" alt="OSX System Information - USB" title="OSX System Information - USB"></a></p>

There are a lot of problems with the CH340 chipset drivers to be found on 3D SE and various forums on the internet. To use this cheap CH340 chip that is used by a number of Arduino compatible (clone) boards to provide USB connectivity (a USB bus converter chip that converts USB bus signals to serial interface) you need to install a correct working driver.
For Mac OS X you can try to download a working version for the OS system you are using. You can try to use
this driver installer
or
this driver installer
. Both reported to work with Mac OS.
Edit
: If you are using OSX El Capitan, please read
this
. To  get the CH340 drivers to work you need to use the tool
csrutil
.
Reboot and press CMD+R immediately after hearing the startup sound to boot to Recovery Mode
Open Terminal
Execute the following command:
```
csrutil enable --without kext
```
Reboot
More information is found
here
!