Best time
We were pleasantly surprised on arrival at the Midtown (after reading some of the previous reviews we weren’t expecting much). All staff were extremely pleasant and helpful while booking in and for the duration of our stay. We had a problem with our return transfers (booked with the holiday) and the Concierge and Front Desk were so helpful. 
Our room was really spacious, comfortable beds and very clean, small bathroom with plenty of towels. We had no problem with noise, in or outside the hotel, we were at the front.
The best thing about the Midtown is it’s location. It’s in Back Bay, which is a really nice neighbourhood, right opposite the Christian Science Centre (well worth a visit to the Mapparium), and two minutes from the Prudential Centre. Copley Square, Newbury Street and Boyslton Street with shops and eating places minutes away. There are a few T stations just up the road (really easy to use the underground) and the Old Town Trolley Bus stops opposite the Prudential Centre, useful for sightseeing and as transport. We were so tired by the evening so it was great to be near the Prudential Centre, where we normally ate but there are other places close.
This hotel was excellent for us, it’s an affordable central hotel, a great base to explore Boston. We would definitely stay at this hotel if we were to visit Boston again.