Never again!
My husband and I arrived here on 10 June and were allocated a room on 15th floor. From the start the room was a real disappointment - dark and dingy and there was a strange smell. There were stains on the curtain valance. Within a short time the ants came out to play on the bedside table!! My immediate instinct was to check out but it was late on the Sunday evening. My husband contacted reception who offered to move us to another room on 15th floor which we did. It was slightly better in terms of cleanliness and it had no resident livestock!
The person at the reception desk said the manager would contact us the next day. Did we hear from this person? NOT AT ALL.
We did stay for the 4 nights but were glad to leave and will never return to this Holiday Inn Express. 
As Priority Club members we have stayed at 2 other Holiday Inn Express locations in Manhattan to our entire satisfaction. This one falls far below the standard. Having a large footfall is no excuse for the lack of cleanliness in this hotel.