Trendy boutique hotel near Magnificent Mile
I stayed at the Acme over Thanksgiving weekend. If you are driving, the hotel is easily accessed off the I-94 Ohio St exit & has convenient parking with in/out privileges nextdoor. If you won't have a car during your stay, the hotel is at the intersection of State & Ohio, so you are also steps away from the CTA Red Line (which runs under State St). 
Pros: Great location, unique stylish experience without breaking the bank, helpful staff, easy self-parking, complementary coffee service delivered to your room in the morning. 
Cons: I can't believe a place that seems to cater to a young, hipster / Euro tourist crowd doesn't have recycling! Suggestion box: management, please follow the lead that I have seen in other major cities & consider adding a small recycling bin for glass/aluminum/plastic in your rooms. Also, rooms have iPhone4-friendly speakers, but you'll need an adapter as of 11/2012 to use your iPhone5 with the equipment.