Great for a grad student!
I stayed at the Club Quarters for a little over a week while working through my first residency at Northeastern University. The university had a deal for a cut rate for them for the residency students that missed the "boat" on campus housing. 
It was a great place for me to work and sleep. The room was clean, comfortable and appointed for me to stock some snacks and light meals and also work on my doctoral work. It is just a few blocks from all the interest an Fanuiel (sp?) Hall. I got around the city all week long on a week long T pass and had no issues. The restaurant (Elephant and Castle) attached to the Club Quarters had the BEST fish and chips EVER! The only thing I'll say about staying in the financial district is that the streets roll up at 9ish. I worked late in the room one night and when I decided I needed a break and something to eat basically it was dark, deserted and very quiet walking out around 9-10pm by myself. I did find a Wendy's just a block or two away that was in the process of closing. If you're intending to enjoy the nightlife in Boston, this isn't a convenient place for that, but as a working hotel for me, for the week....it was great.