River Hotel=Club Quarters Wacker
We had booked a standard room at Club Quarters Wacker which we found is located in the River Hotel. We were offered an upgrade to a Junior Suite for just $20 per night so checked out both rooms. The standard, although nicely appointed, was so small there was literally NO place to even put a suitcase and looked out directly at a brick wall. The Jr. Suite was amazing with lots of room, a sofa, desk, refrigerator, microwave and couple of chairs and had an impressive view of the river and the city. Well worth the extra $20 per night!
A comfortable bed, soft, abundant pillows and a good shower are high on my list of what makes a great stay and I'm happy to say they all scored high points from me. The location was prime, just steps from Million Dollar mile and also the theater district. There are an abundance of restaurants, both expensive and budget right in the neighborhood. We ordered pizza at Baccino's at the hotel and were really disappointed but the pasta looked great and the service was good. 
One just slightly annoying thing about the hotel is that it requires using your room key to access your floor in the elevator. This can be difficult sometimes if your hands are full and it can be very temperamental if you don't insert your card just so. However all the good things, like complimentary filtered water dispenser with bottles, Kuerig coffee machines and an office area with free use of printer certainly out weigh the little irritations.
We consider this hotel a real unknown gem and will definately stay here again.