The worst Motel 6 of all time
I stay at the Van Nuys, Sepulveda Blvd Motel 6 from time to time because if I have a very late arrival into Van Nuys, and an early departure on the Fly Away all for work. It is always my very last choice. The rooms are filthy, the hotel clientele is bottom of the barrel. 
So far I have had no security issues with parking inside the compound, so the place serves its purpose for a quick shower and a short sleep close to the Fly Away and the LA/Valley/Hollywood area hell-hole. The desk clerks however have always been very nice. 
This motel is last choice - if you stay at Motel 6's go for Canoga Park or even Sylmar if you can. 
Know before hand that it is a dump and that's what you are getting for $60/night plus or minus.