Great front desk staff, horrible rooms.
I read the reviews here on TripAdvisor prior to booking a room with a Radisson email promo for 25% off and got Petite Room for a rate of $145.45 (including taxes). When I called on the arrival date the hotel couldn't find my reservation - it turned out that I had mistakenly booked the room for the previous week. I told them it was an honest mistake on my part and asked whether they can still refund my money for my mistake, she said no; however, she was able to give me a $150+ tax rate ($175.62 including taxes) for that night, and gave me an upgrade to a Lexington Suite with free breakfast. She noted that the going rate that evening was $300 a night, so it was 50% off. I was still thankful and showed up at the hotel. The lobby was very welcoming. Mariya (sp) checked me in quickly - and after hearing my story she really wanted to make sure I had a good stay - and gave me 2 drink vouchers as well. 
The problem was when I walked into my room. It was a very, very old room with bubbles on the wallpaper, dented furnace, cracks on the walls, black smoke marks around the vent above and there was even a smell in the bathroom. The "suite" was a large room with one bed, one sofa, two full bathrooms and lots of space in between. It was really difficult to imagine how the hotel could charge customers $300 a night for this, even with the location? Because I had to run across town to meet a friend I had to go. Note that I paid $349 (just under $400 with taxes) at the Intercontinental on Times Square just the night before for a new room.
I didn’t have time to say anything about this until early morning at around 3:30am with Mr Martinez when I had to send my friend off. Mr Martinez noted that he does understand that the rooms are in such conditions, and renovations are coming. However, that does not help the situation at hand for my stay.
He further compared the hotel with other hotels around, and noted the hotel is definitely charging much less. Specifically, he pointed out that the Hyatt across the street was charging $600. Unfortunately, when I called the Hyatt soon after, they said the rate was $329. I can pay the $150 rate that I had, but to charge similar to a new hotel across the street for a room – this was unreasonable. Considering the fact that suites are supposed to be better than standard or deluxe rooms, I really wonder what the condition of my original room would have been. 
There’s more: after I spoke with Mr Martinez I went back to the elevator and there was the smell of marijuana inside. I did note that when I checked out the next morning.
After I returned home, I filled out the survey and also send a note to the Front Desk Director, Mr Lalkaka, to which I received a response saying that because they already gave me a $150 + tax rate they aren't able to do anything else. The funny thing was that he noted that "As discussed, we have not charged you for the first night of your reservation." - yet I didn't receive any refunds. Mr. Sheneman, the General Manager also sent a note saying that ". I feel that Nancy has given you a refund on your original no-show reservation and charged you a fair amount for the room you occupied." Again, still have not seen the "refund".
I sought the help of Radisson's corporate social media team but they couldn't get the hotel to do anything else. I know they really tried. 
So the 100% satisfaction guarantee that is stated on the check-in sleeve? That didn't happen when I brought that up to them.
So overall:
1. Great front desk staff as well as the Bell Staff. 
2. Horrible rooms (see the photos for yourself). I'd come back after renovations are complete. Remember the Hyatt 48Lex sometimes may have the $329 rates. Weekdays it gets very expensive. So if you were to compare the two, I'd easily go with the Hyatt.