Plenty of Personality with a few Quirks
Ahhh, Queen Anne - cookie-cutter you definitely were not.
First the good - you can't help but feel at home with the friendly staff, numerous antiques dotting the interior, a very lovely lounge area, internal staircases and other Victorian-style features throughout. 
It is not the most conveniently located hotel in San Francisco, at least to the main tourist destinations. However, with the city being a great walking town, this was no issue for us. We left our car behind during our second day of our stay and easily made it to destinations on the Embarcadero, South of Market, and so forth. Those with mobility issues will definitely want to either take a cab or transit, as the hotel is located up on a hill.
We had one quirk and one issue with our room. The quirk was the heating unit - for our room, the unit was located in the bathroom, so we had to leave the door open to get heat into the main space. The one issue was the shower - the stopper would not stay in place, thus forcing us into tub baths for the first night. To their credit, the shower issue was fixed as promised when we returned from our travels the next day.
Bed had plenty of sleep and decorative pillows and the mattress seemed to be middle-of-the-road (neither too firm or cushy.)
We did make use of the guest computer to print out our boarding passes for our super-early departure the next night. As we needed a car for other parts of our trip, we were appreciative of the nearby parking lot for hotel guests. However, be mindful that the space is limited - what is not a big lot in the first place has spaces reserved for other neighborhood entities. If you get in super late, you may have to scramble for a space elsewhere. 
Other features they have but did not get to partake in included the breakfast and tea & biscuits, use of a fitness center, and wi-fi access in the public areas.
All things considered, including the fairly good rate we got for booking somewhat off-season, we'd stay here again - a solid three-plus rating for me.