Great if you are trendy and really really good looking. Zoolander's perfect hotel! :)
I love the meatpacking district in NY and have stayed in numerous hotels around the area. From the very best to the average. I chose the Dream when my first choice The Standard was full. I have liked the look of the sister hotel the Maritime for some time but fancied the Dream more when it came to booking.
You know what to expect when the doormen look like models. This is a hotel full of pretty people, both staff and guests. Not a bad thing, but I got the impression the better looking you were the better your service was. On a couple of occasions I observed some less than stellar service given to people who just looked like normal folk.
The room I paid for was one with a view of the Empire State. Nice view and the portholes aren't too small so light does get in, but it's not the lightest of rooms. 
The bed was excellent. Very comfy. The bathroom was ok, shower very nice but a too hip for any use sink annoyed me. Brushing your teeth was not easy! Most of the stuff I spat out I had to clean up myself afterwards!!
Room service was ok. Expensive and based upon the expensive steak house in the hotel. My medium sirloin came to me like a piece of leather. Not what I expect for $80+ dollars. 
These trendy hotels lack some of the simpler things I come to expect in hotels. Ice machines in the property or a coffee machine in the room. The fridge was the usual mini bar crammed full of expensive stuff that you end up eating and drinking when you are slightly drunk. Dangerous! 
I barely got a smile out of anyone the entire time I was and for $400+ a night it's not a lot to ask for. 
The property itself is really attractive, albeit on the very dim side lighting wise. A lot of thought has gone into it and some of the design of the hotel was breathtaking.