Trusted Hampton Inn Quality and Hospitality in Times Square
We spent two nights at at the Hampton Inn Manhattan/Times Square South in mid-May and were quite pleased with our stay. Although we were initially surprised to encounter such a small hotel lobby, only two clerks working the reception desk (check-in/check-out lines can form), typical New York micro-sized rooms (but highly efficient), and two slower-than-molasses antiquated elevators servicing 32 floors (which seemed to stop at every floor), we found everything else much to our liking. 
Our immaculate and blissfully quiet room included all the superb amenities that Hampton Inns are known for including fabulously comfortable beds, wifi, use of an exercise room, and a high quality, abundant, and varied complimentary hot breakfast in the morning. Our concierge was attentive, informative, and hospitable--he took plenty of time with us to make sure we understood directions to sights, was eager to store our luggage when the need arose, and handed out freshly-baked cookies when he felt we needed a pick-me-up after a long day of trekking about the town. 
I can't say enough about the location--the hotel is located on W. 39th Street between 8th and 9th, is two blocks from Penn Station, and four blocks from Time Square and the main subway line 1. From our hotel, we could walk to our Broadway show in the evening and return to our room afterwards on a fully lit and seemingly safe street. The room rates are competitively priced and well worth the luxury of being able to walk to main attractions, shopping, shows, and subway lines. We will definitely return next time we need a place to stay in Manhattan.