3 Dog Night, Pet Hotel
This Hilton Hotel has a GREAT location, nice restaurant and bar and friendly staff, however they ACCEPT ANIMALS! I like dogs and cats pretty much, but for $200.00 plus per night I don't want to sleep in a room next to a Rottweiler or in the room he slept in before ME!! 
SO... if you like to travel with your pets and can afford the price, this is a FANTASTIC place for you. Nice views everywhere, 5 minuets from the great restaurants of Little Italy and the Gas Lamp District. 
GREAT for dog lovers, awful experience for me; lots of dogs.