Location Location Location... The James
We just got back from Chicago and stay at The James located on Ontario. We were two blocks from Michigan Ave (Mag. Mile) and in the center of top of the line resaurants and close to the "EL" The hotel was within a reasonal walk to the navy pier (about 20-30 minutes).. we stopped to shop and eat to and from. 
The staff at the hotel were all great. very helpful. We arrived early and needed two beds in the room, they were pleasantly accommodaiting and everytime we asked questions at the front desk we were treated with respect. They would greet us in the morning on our way out , asking if we needed any directions or assistance, and welcomed us back at night asking if we had a good day. The rooms were very clean and roomy. I was traveling with a teenager, no matter what condition he left it in the AM, when we got back the room was orderly and for the turn down service he got two treats each night. We had a problem with the TV controller one night, called up and within two minute someone was at our door came in and fixed it within minutes. The conciege was knowledgable about the area and had great ideas for local tours and restaurants and were very helpful at making reservations and giving us directs..
Over all this is a great place to stay.