Very good location
Travelodge is right at Harrison Red Line stop on the CTA. Cheap way to get there from O'Hare is to take the Blue Line, change at Jackson, and Harrison is just one stop away in the direction of 95th Street.
I walked to Chicago Insitute of Art, Navy Pier, Aquarium, Field Museum, Willis Tower, and Union Station from the Travelodge so I found the location very handy indeed.
Check-in was a breeze, the young woman was very friendly and accommodating as my friend was coming later so she sorted out all the check-in details. The room was a Deluxe Double Room with Two Double Beds and was a very nice size with a good sized bathroom and kitchenette. I found the bed very nice, it was very soft, and I like that. Yes, the aircon unit is loud so if you can't sleep with loud noises this may be a problem. Neither of us had an issue. The only thing that annoyed me in the hotel is the wait for the elevator. We were on the 10th floor and had to wait a long time to get the elevator each time we used it. But that's nit-picking.
Overall a more reasonably priced downtown hotel you will not get in Chicago and we left feeling like we had a good stay and good deal.