Location, Location, Location
The only reason to stay at Radisson Hotel Fisherman's Wharf is because of the location. From the back of the hotel, you can enter the Fisherman's Wharf very easily. We stayed two nights there, and it was very convenient. The beds were very comfortable as well. And the front desk staff was great.
However, none of the rest of the hotel was worth the high price of staying there. Our room was small. The television didn't work. It took a couple of hours before it was serviced. There are no towel racks to hang a towel if you want to reuse it. The toilet paper holders are located far away from the toilet. The furnishings in the room were about what you would get in a hotel one fourth of the cost anywhere else.
The cost of the parking there is high (most of downtown parking in San Francisco is high, but it seemed higher than most). We had a package than included parking and free breakfast at the Ihop. What we didn't know when we booked it was that the breakfast was specified as bacon, eggs, coffee, etc. And it wasn't too helpful since I'm vegetarian and don't eat bacon, and I am not a coffee drinker.
I'm writing this review from a different hotel in another location (but right next to the ocean with a wonderful view of the ocean). This hotel's room is 3 times as large as the Radisson Hotel Fisherman's Wharf. It has better furnishings. And yet it costs a quarter of what the Radisson did (and it has free parking unlike the Radisson).
So if you have money to burn and like the convenience of being right on the Fisherman's Wharf, then the Radisson Hotel Fisherman's Wharf might be the place to stay. But next time, I would stay someplace far cheaper and nicer and use public transportation to come down to the Fisherman's Wharf.