Mixed feelings...
I stayed at the Whitcomb while attending a conference in SF.
The hotel has a long history and the building is almost 100 years old. If you prefer modern, high tech hotels, I recommend you look elsewhere; but if you're into art deco buildings, you may want to give it a try.
The staff are friendly and chatty. Unfortunately, while I was checking in, there was a long queue, so it took longer than usual.
The hotel is near the Civic Centre and cable car station, and with a BART station immediately outside the hotel entrance, so getting to and from SF International Airport is really easy and inexpensive. Moscone Center is within walking distance, but it is a good 20 minutes away.
For coffee junkies, there's a Starbucks within the building itself, but you need to walk a little further for meals unless you're happy with Burger King, which is across the road.