As Central as one can get
Located on the corner of 53rd and 6th; cannot ask for a better location. Has a Starbucks below, a 24hr Deli opposite; the popular Halal brother shawarma carts right outside and subway entry less than a block away. 
The rooms are comfortably appointed and large enough to accommodate a family of 4 (though the system will not allow you to book more than 2+1). 
The bell hops look like they have been there for ever but surprisingly can lift heavy luggage. It's a high occupancy high turnover bed factory so don't expect high service standards. But it's something I can get used to in New York.