Excellent Hotel and great location
My wife and daughter just spent four nights at the Omni Berkshire place. The staff was very friendly and accomodating. We changed rooms after check in and this was completed hassle free. A roll a way was requested but was not in the room when we returned around 8 pm the first night. I called gues services and within 5 minutes a bed was delivered. There was also a problem with the ice machine on our floor, however ice was delivered to the room promptly when requested. The service in this hotel was absolutely amazing from Doormen to the Manager!
We booked the American Girl package and all the items were delivered as promised! This hotel is only 2 blocks from the American Doll store so making numerous trips is very easy. As Texans, we do not walk anywhere unless our car breaks down and we walked everywhere from this hotel with the exception of the 9/11 Memorial. The hotel is just far enough away from the hustle and bustle but close enough to all the major attractions to walk. We never had any problem with outside noise from the 15th floor. Just to see how loud it was, we opened the window and the difference was amazing.
Some caveats. I was informed the location of the double bed rooms are all directly across from the elevator, thus the reason for the room change. Also, the tv's are mounted on the wall and the sound from the room(s) next door penetrates the walls a bit. Nothing too bad though. Also, this hotel does not have the express check in as other Omni's even though a confirmation of this is sent once the online check in is complete. Finally, there are really not any great "city" views as buildings surround the hotel.
The rooms were very nice and well kept. We had a King room with plenty of space for a roll away. There is only one chair to stretch out in in addition to the desk chair. Most of the sitting was done in the bed. My mother acccompanied us on the trip and had a King room as well but had a nice sofa. The bathrooms were small with little counter space but were very nice and fit our needs just fine. 
I will definitely stay here again when travelling to New York. I highly recommend this hotel.