Good price, great location
We stayed at Club Quarters at the Loop in the beginning of May. We had a good room rate (approximately $160/night), and appreciated that they have cheaper parking than most other hotels. Note that the parking for this hotel is quite far in case accessibility is a concern.
Our room was VERY small. This was okay since we were not in it much, but it did feel a bit claustrophobic. This was compounded by awful air freshener that was used. At least we assume it was air freshener. It smelled like rotten food, and the smell was strongest after every clean. We opened the windows and it dissipated quickly. We weren't there much and didn't have a chance to ask them not to spray which was our fault. 
Other than the smell, the room felt reasonably clean. The staff were very friendly. There was filtered water on each floor with water bottles which was very convenient. Free wi-fi was a huge plus. The hotel was very quiet which was great for sleeping. For us, the location was perfect.
The pub as you come in to the hotel on the right is fantastic. If you need a place to eat while staying, definitely head in.
Overall, this hotel did what we needed it to do. The location was great, and the price was right.