DO NOT STAY HERE - POOR SERVICE IN THE GHETTO
The fact that this hotel is located in the ghetto is the least of your worries. The area is unsafe and we were constantly being hassled as we walked down the street. Crack heads are yelling day in and day out and are constantly taunting people who pass by. 
Upon arrival we were met by a deskman who acted like he had better things to do than serve us. He was unenthusiastic and he looked dishevelled. 
The rooms were dirty to say the least and we were constantly being bit by mosquitos. The shower head had nearly no water pressure, so showering became a real chore. 
Being two young girls we feared for our safety and we were convinced that people were coming in and out of our room. One afternoon we left the lights on, as it gets dark at around 5pm in the winter time. When we returned the lights were off. Being concerned, we approached a hotel worker (middle aged, asian man) who laughed at us when we asked him to check our room for us. Not only that, he scoffed at us from then on whenever we saw him. We didn't feel safe or welcome.
By nightfall we were stranded in our rooms, going outside or returning to the hotel during the dark is too unsafe. 
Unfortunately because of the hotel location and service we will not be returning to Renior - or San Francisco.