Good location... if you like construction
Great location in the Southern part of Manhattan. The rooms were nice and clean. The bed was comfortable. The heating/cooling system and I did battle as the room was too cold and then 15 minutes later it was too warm. 
I had left an item in my room after checkout and realizing that I did not have it, I returned to the hotel. The maid had already placed it on her cart and gave it to me as soon as I asked her if she had seen it. 
I was delighted when I saw I had a corner room... that was until I heard the construction. The hotel is located next to the area under construction for the World Trade Center. As a result, the sound of heavy machinery (either a rivet machine [do they still exist] or some type of jackhammer was present from about 0700 to 1900 every day). Also, due to the 9/11 Memorial, you have tons of tour groups clogging the sidewalks/roads and people do not have a clear destination and just meander around aimlessly. 
I do not have anything specific against the hotel. If you like Marriott hotels, this is a decent place.