Okay for business travelers if your company is footing the bill
I stayed in this hotel for a business trip. It was overpriced for what I received, but I mercifully didn't spend much time there. Overall, it tries very hard to be something it's clearly not. I will likely try to find alternate lodgings the next time I need to travel to Boston. Club Quarters depressed me.
The rooms are tiny. There are no microwaves or fridges, but somehow we're supposed to be impressed by the chilled, purified water in the hallway. My room smelled like the men's cosmetics counter at Macy's, or sitting too close to a low-level brokerage employee on the subway. Likewise, the lounge area downstairs was heavily perfumed, or should I say "cologned." 
The sole window in my unit looked out onto a giant blue neon tube. I expected for the price halfway decent decor, which is typically of minimal concern to me. The hotel appears to have been decorated by a bunch of recent MBA grads who consider Target or IKEA the destination for "sophisticated" interior furnishings. 
Restaurant selection in the neighborhood is dismal; I ended up dining at a Wendy's (the Wendy's around the corner has a great view from the second floor dining area and a charming staff!) in desperation. Breakfast consists of a coffee and tea. 
The positive thing about Club Quarters is its close proximity to the train station and corporate offices. That is all. I didn't encounter bugs, so I suppose this is also a positive.