Great stay
As many have mentioned, this is two hotels in one, we stayed in the Marina tower which was fabulous, great staff from the lobby to the cleaners and waitresses in the bars and restaurants.
Rooms were clean and airy, the view over the Marina was amazing.
Great restaurants and bar, swimming pool in a great posion for the Marina tower.
Have no idea what the other portion of the hotel was like only from reviews read, but can totally recommend the Marina Tower. 
They also have an on site Expedia rep selling cut price tickets for San Diego attractions plus a hotel shuttle that take you to the main areas in town for $1 per day.The average taxi fare each way is around $20 so a pretty good deal and very regular.
All in all a great hotel and if we visit San Diego again we would certainly return there.
A special thank you to Abby in Customer services who made sure we got a good room even though we were arriving late