Still our inner harbor fave
Ten years ago, this place was immaculate. It is still very very nice and is the perfect location for a weekend in Baltimore's Inner Harbor. Directly on Pratt street... there is actually a walkway from the Pratt St pavilion second story to the second story of the Galleria Mall which is connected to the Hotel. It is very close to tons of shopping, museums, and food choices. Within walking distance of Fell's Point, Federal Hill, Powerplant Live, and the famous Lexington market. 
The Hotel has some great views of the harbor. Concierge is very helpful finding your way around for newbies. Rooms are above average size and nicely appointed. I have stayed at several Renaissance Hotels around the country and this is still my favorite. Renaissance is by Marriott. And, if you've never stayed in a Marriott, their beds and linens are legendary. They actually sell the linens(the mattress pad is the best seller...and worth every penny). 
You can usually find great deals through Priceline(4stars). Just know that you will have to upgrade if you want to ensure a good view. The Galleria Mall attached to the hotel has a nice food court area for quick meals. 
Take a walk over to Amicci's in the Italian market or eat the Best crab cake in the world at Faidley's in the Lexington market. Visit Fell's point and walk in the footsteps of Edger Allen Poe(mostly through the same bars he frequented) or head for Dangerously Delicious Pies on Federal Hill. Catch a great show or two or three at Powerplant Live or just relax on the patio and people watch. This area truly had something for everyone. Can't begin to say enough.
We have stayed at each of the 4star hotels in inner harbor and you will not be disappointed with this one. One of my favorite hotels in one of my favorite cities.