Location, Location, Location
This place is in a GREAT location. Fisherman's Wharf, the F-Train and a Cable car line are all within walking distance. 
The staff are friendly and helpful. I never opened a door or carried a heavy bag. The evening wine/pizza reception is a nice touch and the staff are so friendly.
Because of the location, the view we had was of the Wharf and was great, although with the view we also got some noise from the road and the bus stop across the street. Not all rooms will have a view of the wharf though. 
We did not have a car, but found it easy to get from the Amtrak to the F-train to the hotel with our luggage and then back without issue. Buy a Muni pass, it is sooo worth it.
My only complaint besides the noise of the street was the size/cost of the room. We reserved a King Suite for 3-4 people assuming it would be 2 rooms or a room with some separation. It was a room with a King bed and a couch that makes into a bed. Thankfully we only had 2 people in the room after all and even with that it was tight with all of our luggage etc. So if you have more than 2 people you might want to get 2 rooms, but they are pricey, but worth it for the location.