Arizona Biltmore
If you fly to Phoenix and stay at the Biltmore, you really do need to rent a car. The hotel is 3 miles away from the city. There are no nearby shops or tourist attractions you can walk to. It costs $10 each way by cab and there are cabs sitting in the parking lot waiting for fares to pick up. There are 2 restaurants on the premises and shops that are pricey. If you want something more reasonably priced, go to the city where there are many restaurants such as the Cheesecake Factory and a movie theater that serves alcohol and food, or you can just go and sit at the bar for drinks or a meal.
I did not use the spa nor did I eat breakfast since the Seminar we attended provided a continental breakfast and plenty of food.
The grounds are beautiful, has a golf course and the hotel is dated but is still very nice. There is an outdoor sitting area where the smokers congregate. Wait staff is available to bring drinks to you. The multiple buildings that have a number of rooms as well as suites that are individual buildings. There are large conference rooms and a large room used for weddings. 
The hotel has 3 beautiful pools and one water slide without lifeguards. They have a bar where you can sit and drink or you can get something to eat. I forgot my bathing suit so I didn't use the pool.
If you are a jogger or want to walk, there is a path going along the waterway where you can run. I walked this dirt road to see where it went and it goes to a busy two lane road with houses - no stores. 
Interesting that Ronald and Nancy Reagan spent their honeymoon there in 1956. I am sure it was really grand back in those days.