Fantastic Location and Great Rooms
The hotel is in a great location. It is walking distance to shops, restaurants, trams and buses! 
Do not worry about the location of it! 
The room was very clean and modern and had your basic hotel amenities. 
The only thing that may have made my experience at the Nikko Hotel would have been the staff at check in. It was our first time in San Francisco - the staff didn't offer any maps etc and when asked if they could recommend a place to eat, the staff member directed me to concierge to ask such a simple question that she could have answered herself. 
I'm not one to complain about little things like this but one negative point like this almost made me forget about the positives.