Not very ADA-friendly & don't count on room service
I have some mobility issues but I am not in a wheelchair. However, I called ahead to make sure they had an elevator and ADA accessible rooms. They do and did, but they are not the easiest place to get around in. The front doors are very heavy (both sets) and it's quite a struggle to drag one's luggage up some steps and try to negotiate a heavy door too. And they don't help you either in or out with your luggage. Once inside, though, the service was prompt and friendly.
I mentioned I had some mobility issues, which is not evident as I am not in a wheelchair, and was directed to the elevator to the 3rd floor. However, I discovered that my room was across a hall and up and down another set of steep stairs with no elevator. The place was completely booked so I had to make do with the room or try and find somewhere else to stay. If I had been in a wheelchair, I would've been SOL. So make sure you ask whether there are ANY stairs between you and your room. This is one of the rooms with a double bed. 
However, once inside the room, it was nice. It had modern air conditioning and nice beds and bedding. It had a small desk and a flat screen TV as well as a mini-fridge. 
When I was there, the restaurant attached to the B & B was called The Creperie on Newbury. I don't know how long it will be in business given its poor management. My roommate and I found a menu in our room that said The Creperie offered both soup and room service. We called the number and were told (1) there was no soup and (2) no, they didn't offer room service. I called the front desk to inquire why the brochure says they offer room service if they don't, and in a few minutes the front desk called me back to explain that the waitress was short handed that night. So instead of telling us that and saying "we can't offer room service tonight," she just said "no room service" and hung up. So my roommate and I went downstairs to the Creperie and found (1) there was indeed soup that night and (2) they were seriously understaffed. The food was good but it took a long time to get it. So heads up if you are in a hurry or want room service. 
The Creperie is also where breakfast is served in the mornings. by the Newbury Guest House. The breakfast was very good. It featured scrambled eggs with ham, english muffins, plain yogurt, sliced melon, two types of cereal, juice, coffee and tea. Unfortunately it didn't start till 7 a.m., which was a problem for me as I was there for a convention which had a 7 a.m. business meeting. But one of the receptionists got me a bowl of cereal for breakfast one morning about 6:30 which I thought was very nice. 
The Newbury Guest House has free wi-fi and a free computer that it lets its guests use to do things like check-in for flights and check email. They don't charge for the service and they let you print a limited number of pages free.
The rooms needed to have more updated information about local places to eat. We found many of the places listed in the book had gone out of business and/or hadn't been there for a long time.