Great DTLA hotel
I stayed here this past weekend, 5/4, and was absolutely blown away. The negative reviews had me pretty worried, and I was skeptical to choose the Millennium Biltmore for my anniversary stay. 
Let me point out that I live relatively close to DTLA, and frequent it often. The parking rates are standard for any downtown overnight parking. You'll find this is the norm in places like San Francisco as well. Also, for anyone that has even visited a large metropolitan area you'll realize there isn't any reason to be worried about the safety of the area. Homeless people are around but they'll never bother you.
Now on to my review. We stayed in a club level king room on the 10th floor. The bed was super comfortable, the furniture was beautiful, and the view was nice of pershing square It was great with the exception of the bathroom. The bathroom was just okay, could definitely use a renovation but it suited its purpose.
Our room was on the same floor and wing as the club lounge which we really loved. From 5-8 there is complimentary appetizers and wine/beer/soda/evian. It was never crowded and had a really comfortable vibe. You also get continental breakfast when staying on the club floor, while not as good as the evening appetizers, was still a nice touch.
Will definitely return