Unique experience for those looking for something different
My husband and I stayed here back in Spring of 2010. We booked through Expedia and wanted something unique and in a good location. We can stay at a chain hotel any other day but this one appealed to us since it's "historic". It was super easy to get here from the airport using the BART. We arrived early and were given a room with double beds! This was not going to work so we went back down to the desk and the lady accomodated us and gave us a better room. She said it was one of the nicer updated rooms with a king bed. This room was MUCH nicer. We loved the location. We were close to Pier and Embarcadero we walked to/used public transportation. 
The lady at the concierge helped us book a special tour and gave us a map so we were able to get around via BART and trolly. She also set up a hotel pick up to take us back to the airport.
We had a great weekend there and I wouldn't mind staying there again. I felt safe since I was with my husband, but if you are a female staying alone and plan on walking in the evening at night I would consider a different location.