Not as good as expected
My wife and I stayed at the Hilton New York in Manhattan on 14th March for 2 nights prior to a cruise on the Atlantic. 
It is rated a 4 star but I would struggle to give it 2 stars. I am a wheelchair user and accessibility is very poor.
Our travel agent had booked a "handicapped" room but the only concession for a wheelchair was a roll in shower and grab rails by the toilet. The room itself was too small for me to get around. 
I have visited the USA may times and up till now accommodation and services for wheelchair users is usually far better than in the UK. However, this hotel falls far short of what I would class as wheelchair friendly.
The bedrooms (at least the one I was allocated) is not suitable for an independent traveller. I could not reach to hang up clothes in the wardrobe and there was only room for me to wheel into the bedroom up to the first bed and the bathroom. Without assistance the bedroom was of little use.
There is no access to their lobby bar, (it is up a few steps) and the lobby reception desk is very high (about chest level for the average person). I had to strain my neck to see the staff and had to shout to make myself heard. 
Apart from the accessibility, the hotel is not suitable if you wish to eat in the evening.
Food is available from their cafe but only until 2:30pm, after that there is a Starbucks coffee shop open until 5:30pm. 
If you wish to eat after that you can have room service or leave the hotel to find a restaurant or cafe out in the streets. It is really a bed/breakfast hotel.
The hotel was part of a cruise package deal where we flew to, and stayed in, New York for two nights then travelled back to Southampton on the Cunard line, Queen Victoria, which by the way was superb.
I wouldn't recommend this hotel for wheelchair users and only useful for other travellers if they prefer to eat outside of the hotel.