Nice hotel in a VERY busy area
Attended a conference, so did not have much choice for the hotel. Overall, I thought the hotel was very nice. Room was typical for a Marriott - everything was in decent shape (not brand new, but certainly not worn). Only complaint was that it took a very long time for the temperature in the room to adjust. It was 72 when I went to bed...turned it down to 65 to sleep, but it was still 68 when I woke up (keep in mind it was only 45 outside, so cooling the room should have been easy). 
Had drinks at the bar one night - expensive, but it is NYC. 
This hotel is huge...I think over 1,000 rooms, it feels big, but never felt crowded. When you walked outside, however, it was crazy. Literally in the middle of Time Square. I personally would have preferred to be a block or two away from the hustle and people. 
My room was on the 15th floor overlooking Time Square - room was quiet, but I couldn't quite get the drapes to fully cover the flashing lights from outside. 
Paid $279 per night...about the same as other similar hotels in the area (a few less expensive, a few more for the nights I was there).