Great location
Situated on Nob Hill and on the Cable Car route, this is a good base for visiting San Francisco, that said, it does stand at the TOP of the hill from town, so if you are a walker on your travels, this one will get you fit. I stay here regularly for business and am very happy to do so.
Rooms are not huge, but plenty spacious enough,always clean, with excellent beds, well appointed bathrooms, plenty or hanging space, the usual big flat screen TV, Mini Bar, Safe.WiFi thoughout the hotel, though there is a daily charge for this. 
Another reviewer mentioned a room on the first floor, overlooking an alleyway and garbage cans ... I've also experienced a room in this location, didn't appreciate the noise from the early collection service, and bottles being dumped, that said, most hotels have one side facing something less than pleasant, so perhaps on booking, specify that you don't want a room that side. I'm happy to get an inward facing room, I don't spend my time in the room looking much out of the window, so the plus side is no traffic noise from the street or passing Cable Cars, but I can still check out of the window for the weather.
The Hotel has a small restaurant, limited, but quality menu and an excellent selection of Wines, available by the glass . I've always found the service good and staff friendly, polite and helpful. Particular mention to the Concierge staff, always busy, but ever helpful, the doorstaff always have a welcome.
There is a well equipped, reasonable sized Gym on the first floor, open 24 hours (good for those with jetlag.)