Still a charming hotel and great location
We read the reviews on tripadvisor.com prior to our stay here and there were basically correct. The hotel is older and, even on the Club Floor, there are signs of age and lack of investment back into the property. That said, we loved our stay. 
The drive into the property is impressive with immediate and attentive bellman service. 
The current main lobby is beautiful with a quick check-in process. The main elevators require walking up a short flight of stairs but there is a side elevator on the main floor just to the right of the main set of elevators if needed. 
For Los Angeles, our Club Floor room was large and nicely appointed. The bed was wonderfully comfortable. The Biltmore does not any longer include refrigerators or coffee makers in their rooms but they can be requested. There is a small daily charge for a refrigerator. The fridge we ordered was delivered immediately and was extremely quiet. The room was also extremely quite even though we were surrounded by other guests.
For us, the Club Floor was worth the extra cost. It was open for continental breakfast every morning and provided a happy hour with drinks, appetizers and cookies from 5pm to 8pm every day. The hostess and waitress in the club were delightful and tried very hard to please every guest. Since I was visiting family in the Keck Hospital, I could drop in here for a light breakfast to go with great coffee in the morning without having to wait for room service. I also came in for the evening appetizers which made a complete meal for me. 
We did try room service one night - it was delivered quickly and the food was adequate as far as room service meals go. We also ate lunch at the Smeraldi's Restaurant downstairs off of the original hotel lobby. The grilled cheese with tomato soup was exactly what we both needed. I would recommend walking down the block to the Water Grill for an excellent dinner. The Water Grill is in the same block as the hotel and has never failed to impress us.
Now for the not so good - the room we were in was not exactly clean or well maintained. The canopy over the bed was stained on one side, paint was clipped off the bottom of the walls in the bathroom and the bathroom fixtures are dated. Did this ruin our stay? NOT AT ALL!!