Little Italy = Little hotel :)
Room: small & clean. Staff: polite Area: lively & safe Return? YES, but not more than 2-3 days.We stayed for 2 nights in July/12. We definitely wanted to stay in Little Italy after having visited the area last year, also saw the hotel at that time. It stands out like a little boutique hotel. So this year I checked Tripadvisor reviews (mostly positive) before making the reservation. We arrived early (1:00ish) but were told we could not check-in until after 3:00pm -it was pointed out that they'd had a full house and would need time to get free rooms ready...fair enough. (Had a secure locked room where we could safely store our cases). We walked to Hortons Center to do a bit of shopping (its not a short walk) and returned at 4.00. There was still a bit of a wait to check if a room was ready for us (there was a change in reception staff). We had paid for an Argento room; were given #420; top floor, right on the corner intersection, lots of windows. The room is s-m-a-l-l , but it grew on us...lol. The bathroom is also small, has a step-in shower and absolutely clean and fresh. No closet, just an alcove with hooks for hanging, a good size dresser, desk, chair and...bed. Flat screen TV hanging on wall. That's it! The space between the end of the bed and the wall is about 3 ft. 
It can be quite noisy late at night (people walking around) and early morning (traffic/trucks). The train is just a block away but after awhile we did not notice the horn much at all. The cafe next door is great for breakfast, the hotel has a courtyard which leads to the coffee shop...nice place to have your brkfst. 
The area was what we were really after - did not disappoint. Lots of Italian flare; at night the streets are filled with people (couples, families - the goodfellas hanging around the cafe). During a morning stroll we watched a group of lively older guys playing bocce in the local park...cool. The restaurants and delis are authenitic...just like in Italy we bought a bottle of wine, fresh bread, prosciutto and cheese...yum!