Very nearly perfect!
Although we had a great time at the Moore and were VERY happy with the staff, accommodations and location, I can understand some of the issues raised in other reviews, and I think it is fair to mention them because everyone doesn't have the same comfort level. The building is old, the floors are creaky and the neighborhood is a little sketchy in spots (just a little). If you have sensitivities around any of those things, you should weigh that appropriately in your decision about whether to stay at the Moore. 
My two traveling companions and I (all middle-aged women) were not afraid to walk around the area during the day and into the evening (I might have been nervous later at night), and we found the location to be fabulous! Pike Place Market was a couple of blocks away, the Space Needle and the new Chihuly Garden and Glass Museum were in walking distance.
Robert at the front desk hooked us up with excellent food and drink recommendations, and we couldn't have been happier. It's a quirky little hotel that is very clean, friendly and full of charm. The beds are comfy, and if you are on one of the upper floors you have the bonus of lovely views. Round it all out with really reasonable prices and you have an excellent value! We will definitely stay there when we return to Seattle.