Less than satisfactory
We had mixed results with this hotel during a two-night stay. Traveling with our two dogs, we asked for and received a room in the smoke-free section close to an entrance. It was far from clean, and there was a slight odor of cigarette smoke in the bathroom, but we decided to stay there for the night. I mentioned that to a rather indifferent woman at the front desk the next morning when I went down for coffee.
But then, while showering, the smoke became intolerable and my wife requested a change of rooms. Thankfully, general manager John Costlow overheard the conversation and took over. He walked back with my wife, acknowledged the smoke in the hall, apparently coming from an adjacent room, then had another room cleaned for us and removed the charge for one night.
I later learned that Ohio's no-smoking laws, regarding hotels, are largely unenforceable (they apparently are an environmental concern and not a police matter). 
Without Mr. Costlow's intervention, I fear our stay at this La Quinta would have been pretty disappointing. His concern and action were most appreciated. Would we stay there again? Maybe not, considering the condition of our original room and the lack of action from the front desk.