4 star for the price, but nothing special
Clean, inviting, and an excellent location on the water. RIGHT on the the water. Any closer and you are in the harbor. Location is EXCELLENT. But this same hotel 20 miles inland would be 3 stars. The location is the 4 star hero here. No special attention or extras. Kudos to the friendliest valet and housekeeping staff in the world. Meant for the convention trade, next door to the convention center. 
Business Center is in lobby is nice and offers free boarding passes for flights. Free internet in the "pubic" areas, for a fee in your room.
Marina Kitchen has a great breakfast buffet, not too bad at $25. The thick, sweet bacon and cinnamon buns are almost worth the money alone, but it comes complete with coffee and juice and made-to-order omelets, fruits, baked goods, meats, and specialty items! We also had dinner there late when we arrived (11pm).
The pool area has nice fire pit areas and is awesome, but offers no view as a large restaurant is in front of the pool and blocks the marina. Very "tropical" looking pool area. Nice work out facility. No spa. Go to the Hyatt next door for the spa (the Hyatt, a taller building, has a true 4 star lobby, and a great view at the top of the Hyatt bar - go next door for evening drinks).
The room was ample, clean, and had a great shower. Nice bath products, but not 4 star. The bed was a bit soft for a 4 star room.
Nice balcony overlooking the harbor. Request a room overlooking the harbor in the NORTH TOWER. The South TOWER only has a few balconies. The NORTH TOWER has almost 100% balconies. Ask for one facing the marina. The other view is of the city, nice, but we prefer the marina.
Must dos:
THE ZOO, the USS Midway, La Jolla (if you have a car - go snorkeling with the harbor seals), the harbor cruise, dinner in Little Italy or the Gaslamp district).
THIS is a super city. HAVE a great time!
My opinion, book it at $250 or less and you have a "deal."