Nice Hotel, Nice Location
Sir Francis Drake is a nice hotel located in a good & convenient section of Downtown San Francisco. It's only a block away from Union Square, and a short cab ride from embarcadero. Our room was very clean and unexpectedly large. There was plenty of space for the couple that we were traveling in to come to our room and comfortably hang out. The furniture was older but in nice condition, and I expected the bathroom to be a little more recently renovated. However, the bathroom and the room itself were indeed very clean!
If you're looking for a ride on the San Francisco Trolly while in the city, Sir Francis Drake is perfect because the trolly goes right up Powell Street, and the hotel's main entrance is on Powell Street. Another great thing about this place is Scala's Bistro, the restaurant in the hotel. The food here is amazing! I'll be writing a separate review for that, though. Be sure to eat here at least once if you stay at Sir Francis Drake. Actually, eat there even if you don't pick SFD.
The staff is very friendly at Sir Francis Drake. They are also very accomodating. There's a nice bar in the main lobby, and the bartenders are really cool. The jester that hangs outside the front entrance to flag you a cab and help with your luggage is really cool as well. My only complaint is that they charge you (I believe it was $5) to use the computer lounge. Most hotels offer a shared computer/printer complimentary these days.