Not for parents (60+)
I recently booked my parents into the Thompson LES for 4 nights. I think the hotel might have been a bit too edgy for them without the same service levels they're used to, and unfortunately they weren't impressed. My impression of visiting them at the hotel was good though (they asked me to write this review though about some of the things they think could use improvement).
While the hotel is in a great location and is 'hip' with a young crowd in the lobby bar/music lounges downstairs, there were service issues with staying. First, the most unpleasant surprise on arrival was that the bathroom hadn't been cleaned - there was actually residue from a previous occupants party or something all over the walls. My impression of the bathroom, not staying there or having seen what they saw on arrival given the hotel immediately cleaned the bathroom after being alerted, was that the bathroom/shower were large, modern and very cool. 
The next complaint had to do with the buildings fire alarm going off at 7.30am their first morning (they think maybe someone had been smoking in the halls given a strong cigarette smell). While unpleasant, it at least kept them from oversleeping and being late for a meeting.
Also, when having a pre-dinner drink in the lounge on the 1st floor (one floor up from entry), the hot drinks that were ordered were actually cold.
The last complaint was that the TV wasn't getting clear reception with lots of distortion and low def programming that came in and out.
All in all, I think after the initial surprises they had a decent stay at the hotel even though I don't think they'd ever ask to stay there again. The hotel was helpful and quick to take care of the serious issues that they experienced, but for a higher ranking the hotel shouldn't have had these problems in the first place. I think a younger crowd (35 and under) would enjoy the 'coolness' of a stay here though...just not for everyone.