Great location and generally a good hotel
I stayed here recently with my partner who was on business in New York. My first impression of the room wasn't that great - they do feel a little stark and functional, but as our stay went on we really warmed to the decor and 'got' the thinking behind it. 
We had room 72 which looked over the street and gave a good view of some of the skyscrapers nearby. The hotel is located literally just off Fifth Avenue giving easy access to Times Sqaure, Central Park and of course some fantastic shopping (if arriving onto Fifth by the Subway as I did then use Abercrombie and Fitch as your turning reference as the hotel is right past the side of their 5th Ave store).
Despite my initial dislike of the room it has to be said that for a standard room in New York (or any city for that matter) it was a fantastic size. It was also spotlessly clean with lots of storage and a very comfy queen bed. Our bathroom had just the rainhead shower, which was the best I've ever used - spacious with great water pressure and you could be easily tempted to stay in all day.
We had room service breakfast a couple of times during the stay. The oatmeal with fruit was absolutely delicious, however the hot traditional breakfast items were just okay. The first day I ordered expresso with brekafast to stave off the jet lag and by the time it arrived it was stone cold. Simple things like butter were forgotten on another occassion, and the toast per slice was tiny, simple mistakes and downfalls but let me tell you this doesn't come cheap! By the time they've added everybody's cut on and all the different percentage charges our breakfast came to near on $70 so watch out for that. With Starbucks at the end of the street and so many other options I think it might be worth eating breakfast out.
Another disappointment for us was the hotel's dry cleaning facility. I didn't opt for the same day option for a jacket I needed to be cleaned so paid for the lesser priced overnight option - however the jacket was back within five hours. Great you might say, under promise and over deliver; the jacket however felt slightly damp (dry clean?!) smelt strongly of a fishy smell that just wouldn't budge and not only was it ironed really badly but we've snce realised that it has shrunk! All for the bargain price of $15.
All encounters with the staff were friendly, and a problem with our in-room safe was dealt with speedily. Take time to find all of your light switches before settling down for the night as they're not all controlled by the switches beside the bed which is a little frsutrating.
One final thing to watch out for - my partner asked for a cab to JFK to be organised for our last day, however when it showed up it was infact a car with a driver. Nice touch until you relaise that it's over $30 more expensive than a cab ($90!). Also as the journey was on company expenses we had to pay by card - to say that the driver was less than impressed is an undertstement as he said that the hotel had told him that it would be a cash fare.
Over all, despite the negatives I did feel relaxed and at home at the hotel. A few small issues need tidying up to make what is a good hotel now, an excellent one in the future. Would I long to return to Chambers or choose it for a break to NY? Probably not.