Classic Hotel in the Center of San Francisco
I love this hotel, it is so old, classic, and historic. Say in the old wing, the rooms have so much character even if they are smaller. 
From this location you can walk out the front door and get anywhere. The cable car, best shopping in San Fran, walk to china town or Columbus Ave.
Food at this hotel is expensive and so, so, my only complaint. I'd walk out the door and go anywhere else for drinks and dinner including breakfast.