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metadata
dataset_info:
  features:
    - name: x
      dtype: string
    - name: 'y'
      dtype: float32
    - name: targets
      dtype: string
    - name: aso_sequence_5_to_3
      dtype: string
    - name: inhibition_percent
      dtype: float32
    - name: chemistry_json
      dtype: string
    - name: custom_id
      dtype: string
    - name: target_mrna
      dtype: string
    - name: target_gene
      dtype: string
    - name: cell_line
      dtype: string
    - name: cell_line_species
      dtype: string
    - name: dosage
      dtype: float32
    - name: cells_per_well
      dtype: float32
    - name: transfection_method
      dtype: string
    - name: steric_blocking
      dtype: bool
  splits:
    - name: train
      num_bytes: 110977411
      num_examples: 190927
  download_size: 10132302
  dataset_size: 110977411
configs:
  - config_name: default
    data_files:
      - split: train
        path: data/train-*

Citation

This dataset is derived from the ASO Atlas resource introduced in Hill et al. (2025). If you use this dataset, please cite:

@article{hill2025accurately,
  title={Accurately modelling RNase H-mediated antisense oligonucleotide efficacy},
  author={Hill, Barney and Jaques, Maisie R and Nair, Remya R and Whiffin, Nicola and Wood, Matthew JA and Sanders, Stephan J and Oliver, Peter L and Hill, Alyssa C and Rinaldi, Carlo},
  journal={bioRxiv},
  pages={2025--10},
  year={2025},
  publisher={Cold Spring Harbor Laboratory}
}

Source

GitHub: https://github.com/barneyhill/aso_atlas